Glycine--tRNA Ligase (GARS-1) (AA 531-739) antibody
Quick Overview for Glycine--tRNA Ligase (GARS-1) (AA 531-739) antibody (ABIN5697760)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 531-739
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Purpose
- GARS1 antibody
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Immunogen
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Immunogen sequence: 531-739aa
Immunogen: glycyl-tRNA synthetase
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Isotype
- IgG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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human brain tissue were subjected to SDS PAGE followed by western blot with FNab03347(GARS antibody) at dilution of 1:500
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months
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Expiry Date
- 12 months
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- Glycine--tRNA Ligase (GARS-1)
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Alternative Name
- GARS1
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Background
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Synonyms: Glycine--tRNA ligase|Diadenosine tetraphosphate synthetase (Ap4A synthetase)|Glycyl-tRNA synthetase (GlyRS)|Glycyl-tRNA synthetase 1|GARS1|GARS
Background: This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
- 75-80 kDa
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Gene ID
- 2617
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UniProt
- P41250
Target
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